Statement of Principles concerning acute myeloid leukaemia No. 36 of 2006 (Cth)
Statement of Principles
concerning
ACUTE MYELOID LEUKAEMIA
Instrument No. 36 of 2006 as amended
made under section 196B(3) of the
Veterans’ Entitlements Act 1986
This compilation was prepared on 20 July 2011 taking into account Amendment of Statement of Principles concerning ACUTE MYELOID LEUKAEMIA (Instrument No. 44 of 2011)
Prepared by the Repatriation Medical Authority Secretariat, Brisbane
Statement of Principles
concerning
ACUTE MYELOID LEUKAEMIA
No. 36 of 2006
for the purposes of the
Veterans’ Entitlements Act 1986
and
Military Rehabilitation and Compensation Act 2004
Title
This Instrument may be cited as Statement of Principles concerning acute myeloid leukaemia No. 36 of 2006.
Determination
The Repatriation Medical Authority under subsection 196B(3) and (8) of the Veterans’ Entitlements Act 1986 (the VEA):
(a) revokes Instrument No. 170 of 1996; and
(b) determines in its place this Statement of Principles.
Kind of injury, disease or death
(a) This Statement of Principles is about acute myeloid leukaemia and death from acute myeloid leukaemia.
(b)For the purposes of this Statement of Principles, "acute myeloid leukaemia" means a heterogeneous group of malignant neoplasms of haematopoietic cells characterised by a clonal proliferation of myeloid precursor cells, with 20% or more myeloblasts in bone marrow or blood. This definition includes acute promyelocytic leukaemia, acute myelomonocytic leukaemia, acute monoblastic and monocytic leukaemia, acute erythroid leukaemia, acute megakaryoblastic leukaemia, acute basophilic leukaemia, acute panmyelosis with myelofibrosis, and myeloid sarcoma.
Basis for determining the factors
On the sound medical-scientific evidence available, the Repatriation Medical Authority is of the view that it is more probable than not that acute myeloid leukaemia and death from acute myeloid leukaemia can be related to relevant service rendered by veterans or members of the Forces under the VEA, or members under the Military Rehabilitation and Compensation Act 2004 (the MRCA).
Factors that must be related to service
Subject to clause 7, at least one of the factors set out in clause 6 must be related to the relevant service rendered by the person.
Factors
The factor that must exist before it can be said that, on the balance of probabilities, acute myeloid leukaemia or death from acute myeloid leukaemia is connected with the circumstances of a person’s relevant service is:
(a)smoking at least 15 pack years of cigarettes or the equivalent thereof in other tobacco products before the clinical onset of acute myeloid leukaemia and where smoking has ceased, the clinical onset has occurred within five years of cessation; or
(b)having myelodysplastic disorder immediately before the clinical onset of acute myeloid leukaemia; or
(c)undergoing a course of chemotherapy, where the course of chemotherapy commenced at least six months before the clinical onset of acute myeloid leukaemia and where that therapy has ceased, the clinical onset occurred within twenty years of cessation; or
(d)having received a cumulative equivalent dose of at least 0.05 sievert of ionising radiation to the bone marrow at least two years before the clinical onset of acute myeloid leukaemia; or
(e)undergoing treatment with radioactive iodine for cancer before the clinical onset of acute myeloid leukaemia, where the first exposure occurred at least two years before the clinical onset of acute myeloid leukaemia; or
(f)undergoing treatment with radioactive phosphorus for a myeloproliferative disorder before the clinical onset of acute myeloid leukaemia, where the first exposure occurred at least two years before the clinical onset of acute myeloid leukaemia; or
(g)being exposed to benzene on at least 750 days within a continuous five year period before the clinical onset of acute myeloid leukaemia, where:
(i)the first exposure occurred more than ten years before the clinical onset of acute myeloid leukaemia; and
(ii)where the clinical onset occurs within thirty years of that period; or
(h)receiving greater than 40 ppm-years of cumulative exposure to benzene before the clinical onset of acute myeloid leukaemia, where the first exposure occurred more than ten years before the clinical onset of acute myeloid leukaemia and where the clinical onset occurs within thirty years of that exposure; or
(i)inhaling, ingesting or having cutaneous contact with AVGAS or petroleum products containing benzene greater than 5% by volume on more days than not over a continuous period of at least six months, where the first exposure occurred at least ten years before the clinical onset of acute myeloid leukaemia; or
(j)inability to obtain appropriate clinical management for acute myeloid leukaemia.
Factors that apply only to material contribution or aggravation
Paragraph 6(j) applies only to material contribution to, or aggravation of, acute myeloid leukaemia where the person’s acute myeloid leukaemia was suffered or contracted before or during (but not arising out of) the person’s relevant service.
Inclusion of Statements of Principles
In this Statement of Principles if a relevant factor applies and that factor includes an injury or disease in respect of which there is a Statement of Principles then the factors in that last mentioned Statement of Principles apply in accordance with the terms of that Statement of Principles as in force from time to time.
Other definitions
For the purposes of this Statement of Principles:
"a course of chemotherapy" means treatment of a malignant or proliferative disorder with the regular systemic administration of:
(a)an alkylating agent; or
(b)a topoisomerase II inhibitor;
"being exposed to benzene" means:
(a)inhaling benzene vapour where such exposure occurs at an ambient 8-hour time-weighted average benzene concentration exceeding five parts per million;
(b)having cutaneous contact with liquids containing benzene; or
(c)ingesting liquids containing benzene;
"cumulative equivalent dose" means the total dose of ionising radiation received by the particular organ or tissue. The formula used to calculate the cumulative equivalent dose allows doses from multiple types of ionising radiation to be combined, by accounting for their differing biological effect. The unit of equivalent dose is the sievert. For the purposes of this Statement of Principles, the calculation of cumulative equivalent dose excludes doses received from normal background radiation, but includes therapeutic radiation, diagnostic radiation, cosmic radiation at high altitude, radiation from occupation-related sources and radiation from nuclear explosions or accidents;
"death from acute myeloid leukaemia" in relation to a person includes death from a terminal event or condition that was contributed to by the person’s acute myeloid leukaemia;
"pack years of cigarettes, or the equivalent thereof in other tobacco products" means a calculation of consumption where one pack year of cigarettes equals twenty tailor made cigarettes per day for a period of one calendar year, or 7300 cigarettes. One tailor made cigarette approximates one gram of tobacco or one gram of cigar or pipe tobacco by weight. One pack year of tailor made cigarettes equates to 7300 cigarettes, or 7.3 kg of smoking tobacco by weight. Tobacco products means either cigarettes, pipe tobacco or cigars smoked, alone or in any combination;
"ppm-years" means parts per million multiplied by years of exposure;
"relevant service" means:
(a) eligible war service (other than operational service) under the VEA; or
(b) defence service (other than hazardous service) under the VEA; or
(c) peacetime service under the MRCA;
"terminal event" means the proximate or ultimate cause of death and includes:
(a) pneumonia;
(b) respiratory failure;
(c) cardiac arrest;
(d) circulatory failure; or
(e) cessation of brain function;
"8-hour time-weighted average" means the averaging of different exposure levels to benzene during an average exposure period equivalent to eight hours.
Application
This Instrument applies to all matters to which section 120B of the VEA or section 339 of the MRCA applies.
Date of effect
This Instrument takes effect from 30 August 2006.
Notes to Statement of Principles concerning ACUTE MYELOID LEUKAEMIA (Instrument No. 36 of 2006)
The Statement of Principles concerning acute myeloid leukaemia (Instrument No. 36 of 2006) in force under section 196B(3) of the Veterans’ Entitlements Act 1986, as shown in this compilation is amended as indicated in the Tables below.
Table of Instruments
| Title | Date of FRLI registration | Date of | Application, saving or |
| Statement of Principles concerning acute myeloid leukaemia (Instrument No. 36 of 2006) | 23 August 2006 F2006L02751 | 30 August 2006 | |
| Amendment of Statement of Principles concerning acute myeloid leukaemia (Instrument No. 44 of 2011) | 13 May 2011 F2011L00746 | 25 May 2011 |
Table of Amendments
| ad. = added or inserted am. = amended rep. = repealed rs. = repealed and substituted | |
| Provision affected | How affected |
| Clause 6(d) | rs. Instrument No.44 of 2011 |
| Clause 6(e) | rs. Instrument No.44 of 2011 |
| Clause 6(f) | rs. Instrument No.44 of 2011 |
| Clause 9 – "cumulative equivalent dose" | rs. Instrument No.44 of 2011 |
| Clause 9 – "a course of therapeutic radiation" | rep. Instrument No.44 of 2011 |
| Clause 9 – "atomic radiation" | rep. Instrument No.44 of 2011 |
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