National Health (Listing of Pharmaceutical Benefits) Amendment Instrument 2011 (No. 12) (No. PB 83 of 2011) (Cth)

Case

PB 83 of 2011

National Health (Listing of Pharmaceutical Benefits) Amendment Instrument 2011
(No.12)1


National Health Act 1953

I, FELICITY McNEILL, Acting First Assistant Secretary, Pharmaceutical Benefits Division, Department of Health and Ageing, delegate of the Minister for Health and Ageing, make this Instrument under sections 84AF, 85, 85A, 88 and 101 of the National Health Act 1953.

Dated 22 November 2011

FELICITY McNEILL

Acting First Assistant Secretary

Pharmaceutical Benefits Division

Department of Health and Ageing

1          Name of Instrument

(1)        This Instrument is the National Health (Listing of Pharmaceutical Benefits) Amendment Instrument 2011 (No. 12).

(2)        This Instrument may also be cited as PB 83 of 2011.

2          Commencement

This Instrument commences on 1 December 2011.

3          Amendment of the National Health (Listing of Pharmaceutical Benefits) Instrument 2010 (PB 108 of 2010)

Schedule 1 amends the National Health (Listing of Pharmaceutical Benefits) Instrument 2010 (PB 108 of 2010).

Schedule 1     Amendments

  1. Subsections 5(2), 5(3) and 5(4), and notes to 5(2) and 5(4)

substitute

(2)        For subparagraph 85(2)(b)(i) of the Act, paragraph 85(2)(b) of the Act applies to a listed drug mentioned in subparagraph (1)(a)(ii).

(3)        For subparagraph 85(2)(b)(ii) of the Act, paragraph 85(2)(b) of the Act applies to an additive mentioned in Part 2 of Schedule 2.

Note           Part VII of the Act applies to medicinal preparations composed of 1 or more listed drugs mentioned in subsection (2) and 1 or more of the additives mentioned in subsection (3) – see paragraph 85(2)(b) of the Act.

  1. Subsection 20(1), and note to subsection 20(1)

substitute:

(1)        For subsection 85 (2A) of the Act, if the letter D is mentioned in the column headed ‘Section 100 only’ in Schedule 1 for a listed drug, the drug can only be supplied under special arrangements under section 100 of the Act.

  1. Schedule 1, entry for Alendronic Acid in the form Tablet 70 mg (as alendronate sodium)

omit from the column headed “Circumstances” (all instances):

C2645

insert in numerical order:

C3933

  1. Schedule 1, entry for Alendronic acid with colecalciferol

omit from the column headed “Circumstances” (all instances):

C2645

insert in numerical order:

C3933

  1. Schedule 1, entry for Alendronic acid with colecalciferol and calcium

omit from the column headed “Circumstances” (twice occurring):

C2645

insert in numerical order:

C3933

  1. Schedule 1, entry for Arsenic

substitute:

Arsenic Injection concentrate containing arsenic trioxide 10 mg in 10 mL Injection Phenasen PL

MP

See Note 1

C3150 C3891 See Note 3 See Note 3 D
  1. Schedule 1, after entry for Artemether with lumefantrine in the form Tablet (dispersible) 20 mg-120 mg

insert:

Asenapine Sublingual wafer 5 mg (as maleate) Sublingual Saphris LU MP NP C1589 C3935 C3936 60 5
Sublingual wafer 10 mg (as maleate) Sublingual Saphris LU MP NP C1589 C3935 C3936 60 5
  1. Schedule 1, entry for Bevacizumab

substitute:

Bevacizumab Solution for I.V. infusion 100 mg in 4 mL Injection Avastin RO

MP

See Note 1

C3430 C3431 C3894 C3896 See Note 3 See Note 3 D
Solution for I.V. infusion 400 mg in 16 mL Injection Avastin RO

MP

See Note 1

C3430 C3431 C3894 C3896 See Note 3 See Note 3 D
  1. Schedule 1, entry for Bisoprolol in each of the forms: Tablet containing bisoprolol fumarate 2.5 mg; Tablet containing bisoprolol fumarate 5 mg; and Tablet containing bisoprolol fumarate 10 mg

insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Bisoprolol GH GQ MP NP C3234 28 5
  1. Schedule 1, entry for Bleomycin

substitute:

Bleomycin Powder for injection containing bleomycin sulfate 15,000 I.U. Injection Hospira Pty Limited HH

MP

See Note 1

C1139 C1198 See Note 3 See Note 3 D
  1. Schedule 1, entry for Bortezomib

substitute:

Bortezomib Powder for injection 3.5 mg (with any determined brand of sodium chloride injection as the required solvent) Injection Velcade JC

MP

See Note 1

C3762 C3763 C3764 C3765 C3766 C3767 P3764 P3767 See Note 2

4

See Note 2

2

See Note 2

MP

See Note 1

C3762 C3763 C3764 C3765 C3766 C3767

P3762 P3763 P3765 P3766

See Note 2

4

See Note 2

3

See Note 2

  1. Schedule 1, entry for Botulinum Toxin Type Apurified Neurotoxin Complex

substitute:

Botulinum Toxin Type A Purified Neurotoxin Complex Lyophilised powder for injection 100 units Injection Botox AG

MP

See Note 1

See Note 3 See Note 3 See Note 3 See Note 3 D
  1. Schedule 1, entry for Budesonide with Eformoterol in the form Powder for oral inhalation in breath actuated device containing budesonide 400 micrograms with eformoterol fumarate dihydrate 12 micrograms per dose, 60 doses, 2

insert in numerical order in the column headed “Circumstances”:

C2680

  1. Schedule 1, entry for Capecitabine

omit from the column headed “Circumstances” (twice occurring):

C2267

insert in numerical order:

C3942

  1. Schedule 1, entry for Captopril in each of the forms: Tablet 25 mg; and Tablet 50 mg

omit:

Ascent Pharma Pty Ltd GM MP NP 90 5
  1. Schedule 1, entry for Carboplatin

substitute:

Carboplatin Solution for I.V. injection 50 mg in 5 mL Injection Carboplatin Ebewe SZ

MP

See Note 1

See Note 3 See Note 3 D
Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 D
Pfizer Australia Pty Ltd PF

MP

See Note 1

See Note 3 See Note 3 D
Solution for I.V. injection 150 mg in 15 mL Injection Carboplatin Ebewe SZ

MP

See Note 1

See Note 3 See Note 3 D
Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 D
Pfizer Australia Pty Ltd PF

MP

See Note 1

See Note 3 See Note 3 D
Solution for I.V. injection 450 mg in 45 mL Injection Carboplatin Ebewe SZ

MP

See Note 1

See Note 3 See Note 3 D
Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 D
Pfizer Australia Pty Ltd PF

MP

See Note 1

See Note 3 See Note 3 D
  1. Schedule 1, entry for Cetuximab

substitute:

Cetuximab Solution for I.V. infusion 100 mg in 20 mL Injection Erbitux SG

MP

See Note 1

C2713 C2714 C2715 C3843 C3844 C3903 C3904 C3919 C3920 C3921 See Note 3 See Note 3 See Note 3 D
Solution for I.V. infusion 500 mg in 100 mL Injection Erbitux SG

MP

See Note 1

C2713 C2714 C2715 C3843 C3844 C3903 C3904 C3919 C3920 C3921 See Note 3 See Note 3 See Note 3 D
  1. Schedule 1, entry for Cisplatin

substitute:

Cisplatin I.V. injection 10 mg in 10 mL Injection Pfizer Australia Pty Ltd PF

MP

See Note 1

See Note 3 See Note 3 D
I.V. injection 50 mg in 50 mL Injection Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 D
Pfizer Australia Pty Ltd PF

MP

See Note 1

See Note 3 See Note 3 D
I.V. injection 100 mg in 100 mL Injection Cisplatin Ebewe SZ

MP

See Note 1

See Note 3 See Note 3 D
Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 D
Pfizer Australia Pty Ltd PF

MP

See Note 1

See Note 3 See Note 3 D
  1. Schedule 1, entry for Cladribine

substitute:

Cladribine Injection 10 mg in 5 mL Injection Litak OA

MP

See Note 1

C3180 See Note 3 See Note 3 D
Solution for I.V. infusion 10 mg in 10 mL single use vial Injection Leustatin JC

MP

See Note 1

C3180 See Note 3 See Note 3 D
  1. Schedule 1, entry for Codeine with Paracetamol

(a)        omit:

Dolaforte CO MP NP PDP 20 0

(b)        omit:

Dolaforte CO MP NP P2064 60 0
  1. Schedule 1, after entry for Colestipol

insert in the columns in the order indicated:

Corifollitropin Alfa Solution for injection 100 micrograms in 0.5 mL single dose pre-filled syringe Injection Elonva MK

MP

See Note 1

See Note 3 See Note 3 See Note 3 See Note 3 D
Solution for injection 150 micrograms in 0.5 mL single dose pre-filled syringe Injection Elonva MK

MP

See Note 1

See Note 3 See Note 3 See Note 3 See Note 3 D
  1. Schedule 1, entry for Cyclophosphamide

substitute:

Cyclophosphamide Tablet 50 mg Oral Cycloblastin PF

MP

50 2
Powder for injection 500 mg (anhydrous) Injection Endoxan BX

MP

See Note 1

See Note 3 See Note 3 PB
Powder for injection 1 g (anhydrous) Injection Endoxan BX

MP

See Note 1

See Note 3 See Note 3 PB
Powder for injection 2 g (anhydrous) Injection Endoxan BX

MP

See Note 1

See Note 3 See Note 3 PB
  1. Schedule 1, entry for Cytarabine

substitute:

Cytarabine Injection 100 mg in 5 mL vial Injection Pfizer Australia Pty Ltd PF MP
See Note 1
See Note 3 See Note 3 D
  1. Schedule 1, entry for Dalteparin

omit:

Injection containing dalteparin sodium 7,500 I.U. (anti-Xa) in 0.75 mL single dose pre-filled syringe Injection Fragmin PF MP NP 10 1
MP NP P1148 20 3
Injection containing dalteparin sodium 10,000 I.U. (anti-Xa) in 1 mL single dose pre-filled syringe Injection Fragmin PF MP NP 10 1
Injection containing dalteparin sodium 12,500 I.U. (anti-Xa) in 0.5 mL single dose pre-filled syringe Injection Fragmin PF MP NP 10 1

substitute:

Injection containing dalteparin sodium 7,500 I.U. (anti-Xa) in 0.75 mL single dose pre-filled syringe Injection Fragmin PF MP NP 10 1
MP NP P1148 20 3
P3688 30 5
Injection containing dalteparin sodium 10,000 I.U. (anti-Xa) in 1 mL single dose pre-filled syringe Injection Fragmin PF MP NP 10 1
P3688 30 5
Injection containing dalteparin sodium 12,500 I.U. (anti-Xa) in 0.5 mL single dose pre-filled syringe Injection Fragmin PF MP NP 10 1
P3688 30 5
Injection containing dalteparin sodium 15,000 I.U. (anti-Xa) in 0.6 mL single dose pre-filled syringe Injection Fragmin PF MP NP C3688 30 5
Injection containing dalteparin sodium 18,000 I.U. (anti-Xa) in 0.72 mL single dose pre-filled syringe Injection Fragmin PF MP NP C3688 30 5
  1. Schedule 1, after entry for Darunavir in the form Tablet 300 mg (as ethanolate)

insert in the columns in the order indicated:

Tablet 400 mg (as ethanolate) Oral Prezista JC MP
See Note 1
C3940 C3941 120 5 D
  1. Schedule 1, after entry for Denosumab in the form Injection 60 mg in 1 mL pre-filled syringe

insert in the columns in the order indicated:

Injection 120 mg in 1.7 mL Injection Xgeva AN MP NP C1035 C3881 1 5
  1. Schedule 1, entry for Dexamethasone in the form Injection containing dexamethasone sodium phosphate equivalent to 4 mg dexamethasone phosphate in 1 mL

insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Dexmethsone AS MP NP 5 0
  1. Schedule 1, entry for Dexamethasone in the form Injection containing dexamethasone sodium phosphate equivalent to 8 mg dexamethasone phosphate in 2 mL

insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Dexmethsone AS MP NP 5 1
  1. Schedule 1, entry for Diltiazem in each of the forms: Capsule (controlled delivery) containing diltiazem hydrochoride 180 mg; and
    Capsule (controlled delivery) containing diltiazem hydrochoride 240 mg

omit:

Dilzem CD GM MP NP 30 5
  1. Schedule 1, entry for Docetaxel

substitute:

Docetaxel Solution concentrate for I.V. infusion 140 mg in 7 mL Injection Oncotaxel 140 TA

MP

See Note 1

C3186 C3884 C3888 C3890 C3892 C3893 C3916 C3918 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 160 mg in 16 mL Injection DBL Docetaxel Concentrated Injection HH

MP

See Note 1

C3186 C3884 C3888 C3890 C3893 C3916 C3918 See Note 3 See Note 3 D
Powder for I.V. infusion 20 mg with solvent Injection Docetaxel SUN ZF

MP

See Note 1

C3186 C3884 C3890 C3893 See Note 3 See Note 3 D
Powder for I.V. infusion 80 mg with solvent Injection Docetaxel SUN ZF

MP

See Note 1

C3186 C3884 C3890 C3893 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 20 mg in 1 mL Injection Oncotaxel 20 TA

MP

See Note 1

C3186 C3884 C3888 C3890 C3892 C3893 C3916 C3918 See Note 3 See Note 3 See Note 3 D
Taxotere SW

MP

See Note 1

C3186 C3884 C3888 C3890 C3892 C3893 C3916 C3918 See Note 3 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 20 mg in 2 mL Injection DBL Docetaxel Concentrated Injection HH

MP

See Note 1

C3186 C3884 C3888 C3890 C3893 C3916 C3918 See Note 3 See Note 3 See Note 3 D
Docetaxel Ebewe HX

MP

See Note 1

C3186 C3884 C3888 C3890 C3893 C3916 See Note 3 See Note 3 See Note 3 D
Docetaxel Sandoz SZ

MP

See Note 1

C3186 C3884 C3888 C3890 C3893 C3916 C3918 See Note 3 See Note 3 See Note 3 D
Injection set containing 1 single use vial concentrate for I.V. infusion 20 mg (anhydrous) in 0.5 mL with solvent Injection Taxotere SW

MP

See Note 1

C3186 C3884 C3888 C3890 C3892 C3893 C3916 C3918 See Note 3 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 80 mg in 4 mL Injection Oncotaxel 80 TA

MP

See Note 1

C3186 C3884 C3888 C3890 C3892 C3893 C3916 C3918 See Note 3 See Note 3 D
Taxotere SW

MP

See Note 1

C3186 C3884 C3888 C3890 C3892 C3893 C3916 C3918 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 80 mg in 8 mL Injection DBL Docetaxel Concentrated Injection HH

MP

See Note 1

C3186 C3884 C3888 C3890 C3893 C3916 C3918 See Note 3 See Note 3 D
Docetaxel Ebewe HX

MP

See Note 1

C3186 C3884 C3888 C3890 C3893 C3916 See Note 3 See Note 3 D
Docetaxel Sandoz SZ

MP

See Note 1

C3186 C3884 C3888 C3890 C3893 C3916 C3918 See Note 3 See Note 3 D
Injection set containing 1 single use vial concentrate for I.V. infusion 80 mg (anhydrous) in 2 mL with solvent Injection Taxotere SW

MP

See Note 1

C3186 C3884 C3888 C3890 C3892 C3893 C3916 C3918 See Note 3 See Note 3 D
  1. Schedule 1, entry for Doxorubicin

substitute:

Doxorubicin Solution for I.V. injection or intravesical administration containing doxorubicin hydrochloride 10 mg in 5 mL single dose vial Injection/ intravesical Adriamycin Solution PF

MP

See Note 1

See Note 3 See Note 3 D
Doxorubicin Ebewe SZ

MP

See Note 1

See Note 3 See Note 3 D
Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 D
Solution for I.V. injection or intravesical administration containing doxorubicin hydrochloride 20 mg in 10 mL single dose vial Injection/ intravesical Adriamycin Solution PF

MP

See Note 1

See Note 3 See Note 3 D
Solution for I.V. injection or intravesical administration containing doxorubicin hydrochloride 50 mg in 25 mL single dose vial Injection/ intravesical Adriamycin Solution PF

MP

See Note 1

See Note 3 See Note 3 D
Doxorubicin Ebewe SZ

MP

See Note 1

See Note 3 See Note 3 D
Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 D
Solution for I.V. injection or intravesical administration containing doxorubicin hydrochloride 100 mg in 50 mL single dose vial Injection/ intravesical Doxorubicin Ebewe SZ

MP

See Note 1

See Note 3 See Note 3 D
Solution for I.V. injection or intravesical administration containing doxorubicin hydrochloride 200 mg in 100 mL single dose vial Injection/ intravesical Adriamycin PF

MP

See Note 1

See Note 3 See Note 3 D
Doxorubicin Ebewe SZ

MP

See Note 1

See Note 3 See Note 3 D
  1. Schedule 1, entry for Doxorubicin ─ Pegylated Liposomal

substitute:

Doxorubicin – Pegylated Liposomal Suspension for I.V. infusion containing pegylated liposomal doxorubicin hydrochloride 20 mg in 10 mL Injection Caelyx JC MP
See Note 1
C1568 C1795 C1796 C3905 C3910 C3911 See Note 3 See Note 3 D
MP
See Note 1

C1828 C1829 C3348 C3349 4 5 D
Suspension for I.V. infusion containing pegylated liposomal doxorubicin hydrochloride 50 mg in 25 mL Injection Caelyx JC MP
See Note 1
C1568 C1795 C1796 C3905 C3910 C3911 See Note 3 See Note 3 D
  1. Schedule 1, entry for Epirubicin

substitute:

Epirubicin Solution for injection containing epirubicin hydrochloride 10 mg in 5 mL Injection/
intravesical
Epirubicin Ebewe SZ MP
See Note 1
See Note 3 See Note 3 D
Pharmorubicin Solution PF MP
See Note 1
See Note 3 See Note 3 D
Solution for injection containing epirubicin hydrochloride 20 mg in 10 mL Injection/
intravesical
Pharmorubicin Solution PF MP
See Note 1
See Note 3 See Note 3 D
Solution for injection containing epirubicin hydrochloride 50 mg in 25 mL Injection/
intravesical
Epirubicin Ebewe SZ MP
See Note 1
See Note 3 See Note 3 D
Hospira Pty Limited HH MP
See Note 1
See Note 3 See Note 3 D
Pharmorubicin Solution PF MP
See Note 1
See Note 3 See Note 3 D
Solution for injection containing epirubicin hydrochloride 100 mg in 50 mL Injection/
intravesical
Epirubicin Ebewe SZ MP
See Note 1
See Note 3 See Note 3 D
Hospira Pty Limited HH MP
See Note 1
See Note 3 See Note 3 D
Solution for injection containing epirubicin hydrochloride 200 mg in 100 mL Injection/
intravesical
DBL Epirubicin Hydrochloride Injection HH MP
See Note 1
See Note 3 See Note 3 D
Epirubicin Ebewe SZ MP
See Note 1
See Note 3 See Note 3 D
  1. Schedule 1, entry for Etoposide

substitute:

Etoposide Capsule 50 mg Oral Vepesid BQ

MP

20

0

Capsule 100 mg Oral Vepesid BQ

MP

10

0

Solution for I.V. infusion 100 mg in 5 mL vial Injection Etoposide Ebewe SZ MP
See Note 1
See Note 3 See Note 3 PB
Hospira Pty Limited HH MP
See Note 1
See Note 3 See Note 3 PB
Powder for I.V. infusion 100 mg (as phosphate) Injection Etopophos BQ MP
See Note 1
See Note 3 See Note 3 PB
Powder for I.V. infusion 1 g (as phosphate) Injection Etopophos BQ MP
See Note 1
See Note 3 See Note 3 PB
  1. Schedule 1, entry for Famciclovir

omit:

Tablet 500 mg Oral Famvir NV MP NP C3625 C3626 C3627 C3628 C3629 P3625 30 0
Favic 500 QA MP NP C3625 C3626 C3627 C3628 C3629 P3625 30 0
Ezovir AF MP NP C3625 C3626 C3627 C3628 C3629 P3626 P3627 P3628 P3629 56 5
Famvir NV MP NP C3625 C3626 C3627 C3628 C3629 P3626 P3627 P3628 P3629 56 5
Favic 500 QA MP NP C3625 C3626 C3627 C3628 C3629 P3626 P3627 P3628 P3629 56 5

substitute:

Tablet 500 mg Oral APO-Famciclovir TX MP NP C3625 C3626 C3627 C3628 C3629 P3625 30 0
Chem mart Famciclovir CH MP NP C3625 C3626 C3627 C3628 C3629 P3625 30 0
Famvir NV MP NP C3625 C3626 C3627 C3628 C3629 P3625 30 0
Favic 500 QA MP NP C3625 C3626 C3627 C3628 C3629 P3625 30 0
Terry White Chemists Famciclovir TW MP NP C3625 C3626 C3627 C3628 C3629 P3625 30 0
APO-Famciclovir TX MP NP C3625 C3626 C3627 C3628 C3629 P3626 P3627 P3628 P3629 56 5
Chem mart Famciclovir CH MP NP C3625 C3626 C3627 C3628 C3629 P3626 P3627 P3628 P3629 56 5
Ezovir AF MP NP C3626 C3627 C3628 C3629 P3626 P3627 P3628 P3629 56 5
Famvir NV MP NP C3625 C3626 C3627 C3628 C3629 P3626 P3627 P3628 P3629 56 5
Favic 500 QA MP NP C3625 C3626 C3627 C3628 C3629 P3626 P3627 P3628 P3629 56 5
Terry White Chemists Famciclovir TW MP NP C3625 C3626 C3627 C3628 C3629 P3626 P3627 P3628 P3629 56 5
  1. Schedule 1, entry for Fludarabine

substitute:

Fludarabine Tablet containing fludarabine phosphate 10 mg Oral Fludara GZ MP C3015 20 5
Powder for I.V. injection containing fludarabine phosphate 50 mg Injection Farine WQ MP
See Note 1
C3887 See Note 3 See Note 3 PB
Fludara GZ MP
See Note 1
C3887 See Note 3 See Note 3 PB
Fludarabine Actavis TA MP
See Note 1
C3887 See Note 3 See Note 3 PB
Solution for I.V. injection 50 mg fludarabine phosphate in 2 mL Injection Fludarabine Ebewe SZ MP
See Note 1
C3887 See Note 3 See Note 3 PB
  1. Schedule 1, entry for Fluorouracil

substitute:

Fluorouracil Injection 500 mg in 10 mL Injection Fluorouracil Ebewe SZ MP
See Note 1
See Note 3 See Note 3 See Note 3 See Note 3 D
Hospira Pty Limited HH MP
See Note 1
See Note 3 See Note 3 See Note 3 See Note 3 D
Injection 1000 mg in 20 mL Injection DBL Fluorouracil Injection BP HH MP
See Note 1
See Note 3 See Note 3 See Note 3 See Note 3 D
Fluorouracil Ebewe SZ MP
See Note 1
See Note 3 See Note 3 See Note 3 See Note 3 D
Injection 2500 mg in 50 mL Injection DBL Fluorouracil Injection BP HH MP
See Note 1
See Note 3 See Note 3 See Note 3 See Note 3 D
Fluorouracil Ebewe SZ MP
See Note 1
See Note 3 See Note 3 See Note 3 See Note 3 D
Injection 5000 mg in 100 mL Injection Fluorouracil Ebewe SZ MP
See Note 1
See Note 3 See Note 3 See Note 3 See Note 3 D
  1. Schedule 1, entry for Fotemustine

substitute:

Fotemustine Powder for injection 208 mg with solvent Injection Muphoran SE MP
See Note 1
C3181 See Note 3 See Note 3 D
  1. Schedule 1, entry for Ganirelix

omit (second instance):

Orgalutran MK MP
See Note 1
See Note 3 See Note 3 See Note 3 See Note 3 D
  1. Schedule 1, entry for Gemcitabine

substitute:

Gemcitabine Powder for I.V. infusion 200 mg (as hydrochloride) Injection DBL Gemcitabine for Injection HH

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemcitabine Actavis TA

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemcitabine Ebewe SZ

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemcitabine Kabi PK

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemcitabine Sun ZF

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemcite ZP

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemplan WQ

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemzar LY

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 200 mg (as hydrochloride) in 20 mL Injection Gemcitabine Ebewe SZ

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 500 mg (as hydrochloride) in 50 mL Injection Gemcitabine Ebewe SZ

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Powder for I.V. infusion 1 g (as hydrochloride) Injection DBL Gemcitabine for Injection HH

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemcitabine Actavis TA

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemcitabine Ebewe SZ

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemcitabine Kabi PK

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemcitabine Sun ZF

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemcite ZP

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemplan WQ

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemzar LY

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 1000 mg (as hydrochloride) in 100 mL Injection Gemcitabine Ebewe SZ

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Powder for I.V. infusion 2 g (as hydrochloride) Injection DBL Gemcitabine for Injection HH

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
Gemcitabine Kabi PK

MP

See Note 1

C1193 C1194 C1740 C2069 C2141 C3889 C3890 C3906 C3913 C3914 See Note 3 See Note 3 D
  1. Schedule 1, entry for Idarubicin

substitute:

Idarubicin Capsule containing idarubicin hydrochloride 5 mg Oral Zavedos PF

MP

C1006 3 0
Capsule containing idarubicin hydrochloride 10 mg Oral Zavedos PF

MP

C1006 3 0
Solution for I.V. injection containing idarubicin hydrochloride 5 mg in 5 mL Injection Idarubicin Ebewe SZ MP
See Note 1
C1006 See Note 3 See Note 3 PB
Zavedos Solution PF MP
See Note 1
C1006 See Note 3 See Note 3 PB
Solution for I.V. injection containing idarubicin hydrochloride 10 mg in 10 mL Injection Idarubicin Ebewe SZ MP
See Note 1
C1006 See Note 3 See Note 3 PB
Zavedos Solution PF MP
See Note 1
C1006 See Note 3 See Note 3 PB
  1. Schedule 1, entry for Ifosfamide

substitute:

Ifosfamide Powder for I.V. injection 1 g in single dose vial Injection Holoxan BX MP
See Note 1
C1325 C1327 See Note 3 See Note 3 D
Powder for I.V. injection 2 g in single dose vial Injection Holoxan BX MP
See Note 1
C1325 C1327 See Note 3 See Note 3 D
  1. Schedule 1, after entry for Imiquimod

insert:

Indacaterol Capsule containing powder for oral inhalation 150 micrograms (as maleate) (for use in Breezhaler) Inhalation by mouth Onbrez NV MP NP C3883 30 5
Capsule containing powder for oral inhalation 300 micrograms (as maleate) (for use in Breezhaler) Inhalation by mouth Onbrez NV MP NP C3883 30 5
  1. Schedule 1, entry for Interferon Alfa-2a

substitute:

Interferon Alfa-2a Injection 3,000,000 I.U. in 0.5 mL single dose pre-filled syringe Injection Roferon-A RO MP
See Note 1
C1149 C1196 C1234 C3180 C3895 C3899 P1149 P1234
P3180 P3899

15

4

MP
See Note 1
C1149 C1196 C1234 C3180 C3895 C3899

P1196 P3895

15

5

MP
See Note 1
C1463 C3382 C3869 C3870 30

5

C
Injection 4,500,000 I.U. in 0.5 mL single dose pre-filled syringe Injection Roferon-A RO MP
See Note 1
C1196 C1234 C3895 C3899

P1234 P3899

5

4

MP
See Note 1
C1196 C1234 C3895 C3899 P1196 P3895 5 5
MP
See Note 1
C1463 C3382 C3869 C3870 30 5 C
Injection 6,000,000 I.U. in 0.5 mL single dose pre-filled syringe Injection Roferon-A RO MP
See Note 1
C1196 C1234 C3895 C3899 P1234 P3899 5 4
MP
See Note 1
C1196 C1234 C3895 C3899 P1196 P3895 5 5
MP
See Note 1
C1463 C3382 C3869 C3870

30

5 C
Injection 9,000,000 I.U. in 0.5 mL single dose pre-filled syringe Injection Roferon-A RO MP
See Note 1
C1196 C1234 C3895 C3899 P1234 P3899 5 4
MP
See Note 1
C1196 C1234 C3895 C3899 P1196 P3895 5 5
MP
See Note 1
C1463 C3382 C3869 C3870 30 5 C
  1. Schedule 1, entry for Interferon Alfa-2b in the form Solution for injection 18,000,000 I.U.in 1.2 mL multi-dose injection pen

omit:

MP
See Note 1
C1149 C1196 C1206 P1149 3 4
MP
See Note 1
C1149 C1196 C1206 P1196 P1206 3 5

substitute:

MP
See Note 1
C1149 C1196 C1206 C3180 C3895 C3898 P1149 P3180 3 4
MP
See Note 1
C1149 C1196 C1206 C3180 C3895 C3898 P1196 P1206 P3895 P3898 3 5
  1. Schedule 1, entry for Interferon Alfa-2b in the form Solution for injection 30,000,000 I.U. in 1.2 mL multi-dose injection pen

omit:

MP
See Note 1
C1196 C1206 3 5

substitute:

MP
See Note 1
C1196 C1206 C3895 C3898 3 5
  1. Schedule 1, entry for Irinotecan

substitute:

Irinotecan I.V. injection containing irinotecan hydrochloride trihydrate 40 mg in 2 mL Injection Camptosar PF

MP

See Note 1

C3184 See Note 3 See Note 3 D
Hospira Pty Limited HH

MP

See Note 1

C3184 See Note 3 See Note 3 D
Irinotecan Actavis TA

MP

See Note 1

C3184 See Note 3 See Note 3 D
Irinotecan Alphapharm AF

MP

See Note 1

C3184 See Note 3 See Note 3 D
Irinotecan Ebewe SZ

MP

See Note 1

C3184 See Note 3 See Note 3 D
Irinotecan Kabi PK

MP

See Note 1

C3184 See Note 3 See Note 3 D
Omegapharm Irinotecan OE

MP

See Note 1

C3184 See Note 3 See Note 3 D
Tecan WQ

MP

See Note 1

C3184 See Note 3 See Note 3 D
I.V. injection containing irinotecan hydrochloride trihydrate 100 mg in 5 mL Injection Camptosar PF

MP

See Note 1

C3184 See Note 3 See Note 3 D
Hospira Pty Limited HH

MP

See Note 1

C3184 See Note 3 See Note 3 D
Irinotecan Actavis TA

MP

See Note 1

C3184 See Note 3 See Note 3 D
Irinotecan Alphapharm AF

MP

See Note 1

C3184 See Note 3 See Note 3 D
Irinotecan Ebewe SZ

MP

See Note 1

C3184 See Note 3 See Note 3 D
Irinotecan Kabi PK

MP

See Note 1

C3184 See Note 3 See Note 3 D
Omegapharm Irinotecan OE

MP

See Note 1

C3184 See Note 3 See Note 3 D
Tecan WQ

MP

See Note 1

C3184 See Note 3 See Note 3 D
I.V. injection containing irinotecan hydrochloride trihydrate 300 mg in 15 mL Injection Camptosar PF

MP

See Note 1

C3184 See Note 3 See Note 3 D
Irinotecan Ebewe SZ

MP

See Note 1

C3184 See Note 3 See Note 3 D
I.V. injection containing irinotecan hydrochloride trihydrate 500 mg in 25 mL Injection Hospira Pty Limited HH

MP

See Note 1

C3184 See Note 3 See Note 3 D
Irinotecan Actavis 500 TA

MP

See Note 1

C3184 See Note 3 See Note 3 D
Irinotecan Ebewe SZ

MP

See Note 1

C3184 See Note 3 See Note 3 D
  1. Schedule 1, entry for Lacosamide

omit:

Oral solution 15 mg per mL, 200 mL Oral Vimpat UC MP NP C3303 C3304 2 5
  1. Schedule 1, after entry for Lopinavir with Ritonavir

insert:

Losartan Tablet containing losartan potassium 25 mg Oral Cozavan AF MP NP 30 5
Tablet containing losartan potassium 50 mg Oral Cozavan AF MP NP 60 5
  1. Schedule 1, after entry for Macrogol 3350 in the form Powder for oral solution 510 g [your pharmacy Clear Laxative (third instance)]

insert:

Magnesium Tablet 37.4 mg (as aspartate dihydrate) Oral Mag-Sup PP MP NP C3937 C3938 50 5
  1. Schedule 1, entry for Medroxyprogesterone in the form Tablet containing medroxyprogesterone acetate 10 mg

(a)        omit from the column headed “Responsible Person”:                 SZ          substitute:             HX

(b)        insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Medroxyprogesterone Sandoz SZ MP NP 30 2
  1. Schedule 1, entry for Metformin in the form Tablet containing metformin hydrochloride 500 mg

omit:

Glucohexal HX MP NP 100 5
  1. Schedule 1, entry for Metformin in the form Tablet containing metformin hydrochloride 850 mg

omit:

Glucohexal HX MP NP 60 5
  1. Schedule 1, entry for Metformin in the form Tablet containing metformin hydrochloride 1 g

omit:

Glucohexal HX MP NP 90 5
  1. Schedule 1, entry for Methotrexate

substitute:

Methotrexate Tablet 2.5 mg Oral Hospira Pty Limited HH MP 30 5
Methoblastin PF MP 30 5
Tablet 10 mg Oral Methoblastin PF MP 15 3
MP P2884 50 2
Injection 5 mg in 2 mL vial Injection Hospira Pty Limited HH

MP

See Note 1

See Note 2

5

See Note 2

0

See Note 2

Injection 50 mg in 2 mL vial Injection Hospira Pty Limited HH

MP

See Note 1

See Note 2

5

See Note 2

5

See Note 2

Pfizer Australia Pty Ltd PF

MP

See Note 1

See Note 2

5

See Note 2

5

See Note 2

Solution concentrate for I.V. infusion 500 mg in 20 mL vial Injection Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 See Note 3 PB
Solution concentrate for I.V. infusion 1000 mg in 10 mL vial Injection Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 See Note 3 PB
Methotrexate Ebewe SZ

MP

See Note 1

See Note 3 See Note 3 See Note 3 PB
Solution concentrate for I.V. infusion 5000 mg in 50 mL vial Injection Methotrexate Ebewe SZ

MP

See Note 1

See Note 3 See Note 3 See Note 3 PB
  1. Schedule 1, entry for Mitozantrone

substitute:

Mitozantrone Injection 10 mg (as hydrochloride) in 5 mL Injection Pfizer Australia Pty Ltd PF

MP

See Note 1

See Note 3 See Note 3 D
Injection 20 mg (as hydrochloride) in 10 mL Injection Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 D
Mitozantrone Ebewe SZ

MP

See Note 1

See Note 3 See Note 3 D
Onkotrone BX

MP

See Note 1

See Note 3 See Note 3 D
Pfizer Australia Pty Ltd PF

MP

See Note 1

See Note 3 See Note 3 D
Injection 25 mg (as hydrochloride) in 12.5 mL Injection Onkotrone BX

MP

See Note 1

See Note 3 See Note 3 D
Pfizer Australia Pty Ltd PF

MP

See Note 1

See Note 3 See Note 3 D
  1. Schedule 1, entry for Morphine in each of the forms: Tablet containing morphine sulfate 10 mg (controlled release); Tablet containing morphine sulfate 30 mg (controlled release); Tablet containing morphine sulfate 60 mg (controlled release); and Tablet containing morphine sulfate 100 mg (controlled release)

insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

APOTEX-MORPHINE MR TX MP NP C1062 28 0
  1. Schedule 1, entry for Nafarelin

substitute:

Nafarelin Nasal spray (pump pack) 200 micrograms (as acetate) per dose, 60 doses Nasal Synarel PF MP
See Note 1
C1172 C1389
See Note 2
See Note 2 1
See Note 2
5
See Note 2
  1. Schedule 1, entry for Norethisterone with Ethinyloestradiol in the form Pack containing 12 tablets 500 micrograms-35 micrograms,
    9 tablets 1 mg-35 micrograms and 7 inert tablets

omit:

Synphasic PF MP NP 4 2
  1. Schedule 1, entry for Norethisterone with Mestranol

substitute:

Norethisterone with Mestranol Pack containing 21 tablets 1 mg-50 micrograms and 7 inert tablets Oral Norinyl-1/28 PF MP NP 4 2
  1. Schedule 1, entry for Oxaliplatin

substitute:

Oxaliplatin Solution concentrate for I.V. infusion 50 mg in 10 mL Injection DBL Oxaliplatin Concentrate HH

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Eloxatin SW

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin Kabi PK

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin SUN ZF

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Powder for I.V. infusion 50 mg Injection Hospira Pty Limited HH

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxalatin ZP

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin Actavis TA

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin Alphapharm AF

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin Ebewe SZ

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin Link PK

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Xalox WQ

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 100 mg in 20 mL Injection DBL Oxaliplatin Concentrate HH

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Eloxatin SW

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin Kabi PK

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin SUN ZF

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Powder for I.V. infusion 100 mg Injection Hospira Pty Limited HH

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxalatin ZP

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin Actavis TA

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin Alphapharm AF

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin Ebewe SZ

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin Link PK

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Winthrop Oxaliplatin WA

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Xalox WQ

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 200 mg in 40 mL Injection Eloxatin SW

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
Oxaliplatin SUN ZF

MP

See Note 1

C3900 C3901 C3930 C3939 See Note 3 See Note 3 D
  1. Schedule 1, after entry for Oxycodone in the form Suppository 30 mg (as pectinate)

insert:

Oxycodone with naloxone Tablet (controlled release) containing oxycodone hydrochloride 5 mg with naloxone hydrochloride 2.5 mg Oral Targin 5/2.5mg MF MP NP C1062 28 0
Tablet (controlled release) containing oxycodone hydrochloride 10 mg with naloxone hydrochloride 5 mg Oral Targin 10/5mg MF MP NP C1062 28 0
Tablet (controlled release) containing oxycodone hydrochloride 20 mg with naloxone hydrochloride 10 mg Oral Targin 20/10mg MF MP NP C1062 28 0
Tablet (controlled release) containing oxycodone hydrochloride 40 mg with naloxone hydrochloride 20 mg Oral Targin 40/20mg MF MP NP C1062 28 0
  1. Schedule 1, entry for Paclitaxel

substitute:

Paclitaxel Solution concentrate for I.V. infusion 30 mg in 5 mL Injection Anzatax HH

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Paclitaxel Actavis TA

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Paclitaxel Ebewe SZ

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Paclitaxel Kabi PK

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Plaxel WQ

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Taxol BQ

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 100 mg in 16.7 mL Injection Anzatax HH

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Paclitaxel Actavis TA

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Paclitaxel Ebewe SZ

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Paclitaxel Kabi PK

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Plaxel WQ

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Taxol BQ

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 150 mg in 25 mL Injection Anzatax HH

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Paclitaxel Actavis TA

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Paclitaxel Ebewe SZ

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Plaxel WQ

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Solution concentrate for I.V. infusion 300 mg in 50 mL Injection Anzatax HH

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Paclitaxel Actavis TA

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Paclitaxel Ebewe SZ

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Paclitaxel Kabi PK

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Plaxel WQ

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
Taxol BQ

MP

See Note 1

C3186 C3890 C3893 C3902 C3917 C3918 See Note 3 See Note 3 D
  1. Schedule 1, entry for Paclitaxel, nanoparticle albumin-bound

substitute:

Paclitaxel, nanoparticle albumin-bound Powder for I.V. injection containing 100 mg paclitaxel Injection Abraxane TS

MP

See Note 1

C3897 See Note 3 See Note 3 D
  1. Schedule 1, after entry for Paliperidone in the form Tablet 9 mg (prolonged release)

insert in the columns in the order indicated:

I.M. injection (modified release) 25 mg (as palmitate) in pre-filled syringe Injection Invega Sustenna JC MP NP C1589 1 5
I.M. injection (modified release) 50 mg (as palmitate) in pre-filled syringe Injection Invega Sustenna JC MP NP C1589 1 5
I.M. injection (modified release) 75 mg (as palmitate) in pre-filled syringe Injection Invega Sustenna JC MP NP C1589 1 5
I.M. injection (modified release) 100 mg (as palmitate) in pre-filled syringe Injection Invega Sustenna JC MP NP C1589 1 5
I.M. injection (modified release) 150 mg (as palmitate) in pre-filled syringe Injection Invega Sustenna JC MP NP C1589 1 5
  1. Schedule 1, entry for Pemetrexed

substitute:

Pemetrexed Powder for I.V. infusion 100 mg (as disodium heptahydrate) Injection Alimta LY

MP

See Note 1

C2957 C2958 C3885 C3886 See Note 3 See Note 3 D
Powder for I.V. infusion 500 mg (as disodium heptahydrate) Injection Alimta LY

MP

See Note 1

C2957 C2958 C3885 C3886 See Note 3 See Note 3 D
  1. Schedule 1, entry for Perindopril in each of the forms: Tablet containing perindopril erbumine 2 mg; Tablet containing perindopril erbumine 4 mg; and Tablet containing perindopril erbumine 8 mg

insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Perindopril generichealth GQ MP NP 30 5
  1. Schedule 1, after entry for Pramipexole in the form Tablet (extended release) containing pramipexole hydrochloride 1.5 mg

insert in the columns in the order indicated:

Tablet (extended release) containing pramipexole hydrochloride 2.25 mg Oral Sifrol ER BY MP NP C3216 30 5
  1. Schedule 1, after entry for Pramipexole in the form Tablet (extended release) containing pramipexole hydrochloride 3 mg

insert in the columns in the order indicated:

Tablet (extended release) containing pramipexole hydrochloride 3.75 mg Oral Sifrol ER BY MP NP C3216 30 5
  1. Schedule 1, entry for Raltitrexed

substitute:

Raltitrexed Powder for I.V. infusion 2 mg in single use vial Injection Tomudex HH

MP

See Note 1

C3185 See Note 3 See Note 3 D
  1. Schedule 1, entry for Ribavirin and PegInterferon Alfa-2b in each of the forms: Pack containing 112 capsules ribavirin 200 mg and
    4 single use injection pens containing peginterferon alfa-2b powder for injection 50 micrograms with diluent; Pack containing 84 capsules ribavirin 200 mg and 4 single use injection pens containing peginterferon alfa-2b powder for injection 80 micrograms with diluent; and Pack containing 112 capsules ribavirin 200 mg and 4 single use injection pens containing peginterferon alfa-2b powder for injection 100 micrograms with diluent

omit from the column headed “Circumstances”:

C3055  C3413

insert in numerical order:

C3948  C3949

  1. Schedule 1, entry for Rituximab

substitute:

Rituximab Solution for I.V. infusion 100 mg in 10 mL Injection Mabthera RO

MP

See Note 1

C1744 C1745 C2068 C2386 C3908 C3909 C3912 C3915 C3931 C3932 See Note 3 See Note 3 See Note 3 D
Solution for I.V. infusion 500 mg in 50 mL Injection Mabthera RO MP
See Note 1
See Note 3 See Note 3 See Note 3 See Note 3 D

MP

See Note 1

C1744 C1745 C2068 C2386 C3908 C3909 C3912 C3915 C3931 C3932 See Note 3 See Note 3 See Note 3 D
  1. Schedule 1, entry for Roxithromycin in the form Tablet 300 mg [Max Quantity 5; Number of Repeats 0]

(a)        omit from the column headed “Responsible Person”:                 SZ          substitute:             HX

(b)        insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Roxithromycin Sandoz SZ PDP 5 0
  1. Schedule 1, entry for Roxithromycin in the form Tablet 300 mg [Max Quantity 5; Number of Repeats 1]

(a)        omit from the column headed “Responsible Person”:                 SZ          substitute:             HX

(b)        insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Roxithromycin Sandoz SZ MP NP 5 1
  1. Schedule 1, entry for Sertraline in each of the forms: Tablet 50 mg (as hydrochloride); and Tablet 100 mg (as hydrochloride)

(a)        omit from the column headed “Responsible Person”:                 SZ          substitute:             HX

(b)        insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Sertraline Sandoz SZ MP NP C1211 30 5
  1. Schedule 1, entry for Somatropin in each of the forms: Solution for injection 5 mg (15 i.u.) in 1.5 mL cartridge (with preservative); Solution for injection 10 mg (30 i.u.) in 1.5 mL cartridge (with preservative); and Solution for injection 15 mg (45 i.u.) in 1.5 mL cartridge (with preservative)

insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Norditropin FlexPro NO MP
See Note 1
See Note 3 See Note 3 See Note 3 See Note 3 D
  1. Schedule 1, entry for Temozolomide

substitute:

Temozolomide Capsule 140 mg Oral Astromide WQ MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Temizole 140 QA MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Temodal MK MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Astromide WQ MP C1736 C1737 C2100 C2101 P2100 15 2
Temizole 140 QA MP C1736 C1737 C2100 C2101 P2100 15 2
Temodal MK MP C1736 C1737 C2100 C2101 P2100 15 2
Capsule 5 mg Oral Astromide WQ MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Temizole 5 QA MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Temodal MK MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Astromide WQ MP C1736 C1737 C2100 C2101 P2100 15 2
Temizole 5 QA MP C1736 C1737 C2100 C2101 P2100 15 2
Temodal MK MP C1736 C1737 C2100 C2101 P2100 15 2
Capsule 20 mg Oral Astromide WQ MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Temizole 20 QA MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Temodal MK MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Astromide WQ MP C1736 C1737 C2100 C2101 P2100 15 2
Temizole 20 QA MP C1736 C1737 C2100 C2101 P2100 15 2
Temodal MK MP C1736 C1737 C2100 C2101 P2100 15 2
Capsule 100 mg Oral Astromide WQ MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Temizole 100 QA MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Temodal MK MP C1736 C1737 C2100 C2101 P1736 P1737 P2101 5 5
Astromide WQ MP C1736 C1737 C2100 C2101 P2100 15 2
Temizole 100 QA MP C1736 C1737 C2100 C2101 P2100 15 2
Temodal MK MP C1736 C1737 C2100 C2101 P2100 15 2
Capsule 250 mg Oral Astromide WQ MP C1736 C1737 C2101 5 5
Temizole 250 QA MP C1736 C1737 C2101 5 5
Temodal MK MP C1736 C1737 C2101 5 5
  1. Schedule 1, omit entry for Thiotepa

  1. Schedule 1, entry for Topiramate in each of the forms: Tablet 25 mg; and Tablet 50 mg

insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Topiramate generichealth GQ MP NP C2797 C2799 60 5
  1. Schedule 1, entry for Topiramate in each of the forms: Tablet 100 mg; and Tablet 200 mg

insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Topiramate generichealth GQ MP NP C2797 60 5
  1. Schedule 1, entry for Topotecan

substitute:

Topotecan Powder for I.V. infusion 4 mg (as hydrochloride) Injection Hycamtin GK

MP

See Note 1

C3186 See Note 3 See Note 3 D
  1. Schedule 1, entry for Valaciclovir in the form Tablet 500 mg (as hydrochloride) [Max Quantity 30; Number of Repeats 5]

insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Valaciclovir generichealth GQ MP NP C3622 C3623 C3624 C3631 P3623 P3624 30 5
  1. Schedule 1, entry for Valaciclovir in the form Tablet 500 mg (as hydrochloride) [MaxQuantity 42; Number of Repeats 0]

insert in the columns in the order indicated, and in alphabetical order for the column headed “Brand”:

Valaciclovir generichealth GQ MP NP C3622 C3623 C3624 C3631 P3622 P3631 42 0
  1. Schedule 1, entry for Vinblastine

substitute:

Vinblastine Solution for I.V. injection containing vinblastine sulfate 10 mg in 10 mL Injection Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 D
  1. Schedule 1, entry for Vincristine

substitute:

Vincristine I.V. injection containing vincristine sulfate 1 mg in 1 mL Injection Hospira Pty Limited HH

MP

See Note 1

See Note 3 See Note 3 D
Pfizer Australia Pty Ltd PF

MP

See Note 1

See Note 3 See Note 3 D
  1. Schedule 1, entry for Vinorelbine

substitute:

Vinorelbine Capsule 20 mg (as tartrate) Oral Navelbine FB MP C1194 20 2
Capsule 30 mg (as tartrate) Oral Navelbine FB MP C1194 16 2
Solution for I.V. infusion 10 mg (as tartrate) in 1 mL Injection Hospira Pty Limited HH

MP

See Note 1

C3890 C3907 See Note 3 See Note 3 PB
Navelbine FB

MP

See Note 1

C3890 C3907 See Note 3 See Note 3 PB
Vinorelbine Ebewe SZ

MP

See Note 1

C3890 C3907 See Note 3 See Note 3 PB
Solution for I.V. infusion 50 mg (as tartrate) in 5 mL Injection Hospira Pty Limited HH

MP

See Note 1

C3890 C3907 See Note 3 See Note 3 PB
Navelbine FB

MP

See Note 1

C3890 C3907 See Note 3 See Note 3 PB
Vinorelbine Ebewe SZ

MP

See Note 1

C3890 C3907 See Note 3 See Note 3 PB
Vinorelbine Kabi PK

MP

See Note 1

C3890 C3907 See Note 3 See Note 3 PB
  1. Schedule 1, entry for Zoledronic Acid in the form Solution for I.V. infusion 5 mg (as monohydrate) in 100 mL

omit from the column headed “Circumstances”:

C3287  C3288

C3289  C3290

substitute:

C3290  C3945

C3946  C3947

  1. Schedule 3

omit:

CO Chemists’ Own Pty Ltd  45 000 585 197
  1. Schedule 4, Part 1, entry for Alendronic Acid

(a)        omit:

C2645 Treatment as the sole PBS-subsidised anti-resorptive agent for osteoporosis in a patient aged 70 years of age or older with a bone mineral density T-score of -3.0 or less, and where the date, site (femoral neck or lumbar spine) and score of the qualifying bone mineral density measurement are documented in the patient's medical records when treatment is initiated Compliance with Authority Required procedures - Streamlined Authority Code 2645

(b)        insert after existing text in the columns in the order indicated:

C3933 Treatment as the sole PBS-subsidised anti-resorptive agent for osteoporosis in a patient aged 70 years of age or older with a bone mineral density T-score of -2.5 or less, and where the date, site (femoral neck or lumbar spine) and score of the qualifying bone mineral density measurement are documented in the patient's medical records when treatment is initiated Compliance with Authority Required procedures - Streamlined Authority Code 3933
  1. Schedule 4, Part 1, entry for Alendronic acid with colecalciferol

(a)        omit:

C2645 Treatment as the sole PBS-subsidised anti-resorptive agent for osteoporosis in a patient aged 70 years of age or older with a bone mineral density T-score of -3.0 or less, and where the date, site (femoral neck or lumbar spine) and score of the qualifying bone mineral density measurement are documented in the patient's medical records when treatment is initiated Compliance with Authority Required procedures - Streamlined Authority Code 2645

(b)        insert after existing text in the columns in the order indicated:

C3933 Treatment as the sole PBS-subsidised anti-resorptive agent for osteoporosis in a patient aged 70 years of age or older with a bone mineral density T-score of -2.5 or less, and where the date, site (femoral neck or lumbar spine) and score of the qualifying bone mineral density measurement are documented in the patient's medical records when treatment is initiated Compliance with Authority Required procedures - Streamlined Authority Code 3933
  1. Schedule 4, Part 1, entry for Alendronic acid with colecalciferol and calcium

(a)        omit:

C2645 Treatment as the sole PBS-subsidised anti-resorptive agent for osteoporosis in a patient aged 70 years of age or older with a bone mineral density T-score of -3.0 or less, and where the date, site (femoral neck or lumbar spine) and score of the qualifying bone mineral density measurement are documented in the patient's medical records when treatment is initiated Compliance with Authority Required procedures - Streamlined Authority Code 2645

(b)        insert after existing text in the columns in the order indicated:

C3933 Treatment as the sole PBS-subsidised anti-resorptive agent for osteoporosis in a patient aged 70 years of age or older with a bone mineral density T-score of -2.5 or less, and where the date, site (femoral neck or lumbar spine) and score of the qualifying bone mineral density measurement are documented in the patient's medical records when treatment is initiated Compliance with Authority Required procedures - Streamlined Authority Code 3933
  1. Schedule 4, Part 1, entry for Arsenic

substitute:

C3150

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Induction and consolidation treatment of relapsed acute promyelocytic leukaemia (characterised by the presence of the t(15:17) translocation or PML/RAR-alpha fusion gene transcript) in a patient who is arsenic naive at induction

Compliance with Authority Required Procedures
C3891

Where the patient is receiving treatment at/from a Public Hospital

Induction and consolidation treatment of relapsed acute promyelocytic leukaemia (characterised by the presence of the t(15:17) translocation or PML/RAR-alpha fusion gene transcript) in a patient who is arsenic naive at induction

Compliance with Authority Required procedures - Streamlined Authority Code 3891
  1. Schedule 4, Part 1, after entry for Artemether with lumefantrine

insert:

Asenapine C1589 Schizophrenia Compliance with Authority Required procedures - Streamlined Authority Code 1589
C3935 Treatment, for up to 6 months, of an episode of acute mania or mixed episodes associated with bipolar I disorder Compliance with Authority Required procedures - Streamlined Authority Code 3935
C3936 Maintenance treatment, as monotherapy, of bipolar I disorder Compliance with Authority Required procedures - Streamlined Authority Code 3936
  1. Schedule 4, Part 1, entry for Bevacizumab

substitute:

C3430

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Initial PBS-subsidised treatment, in combination with first-line chemotherapy, of a patient with previously untreated metastatic colorectal cancer with a World Health Organisation performance status of 0 or 1, where the patient's dose of bevacizumab does not exceed 5 mg per kg every 2 weeks or 7.5 mg per kg every 3 weeks

Compliance with Authority Required Procedures
C3431

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Continuing PBS-subsidised treatment, in combination with first-line chemotherapy, of a patient with metastatic colorectal cancer who has who has previously been issued with an authority prescription for bevacizumab and who does not have progressive disease and who remains on first-line chemotherapy, where the patient's dose of bevacizumab does not exceed 5 mg per kg every 2 weeks or 7.5 mg per kg every 3 weeks

Compliance with Authority Required Procedures
C3894

Where the patient is receiving treatment at/from a Public Hospital

Initial PBS-subsidised treatment, in combination with first-line chemotherapy, of a patient with previously untreated metastatic colorectal cancer with a World Health Organisation performance status of 0 or 1, where the patient's dose of bevacizumab does not exceed 5 mg per kg every 2 weeks or 7.5 mg per kg every 3 weeks, and where the patient's WHO performace status and body weight is recorded in the patient's medical records at the time the treatment cycle is initiated

Compliance with Authority Required procedures - Streamlined Authority Code 3894

C3896

Where the patient is receiving treatment at/from a Public Hospital

Continuing PBS-subsidised treatment, in combination with first-line chemotherapy, of a patient with metastatic colorectal cancer who has previously received PBS-subsidised treatment with bevacizumab and who does not have progressive disease and who remains on first-line chemotherapy, where the patient's dose of bevacizumab does not exceed 5 mg per kg every 2 weeks or 7.5 mg per kg every 3 weeks, and where the patient's body weight is documented in the patient's medical records at the time the treatment cycle is initiated

Compliance with Authority Required procedures - Streamlined Authority Code 3896

  1. Schedule 4, Part 1, entry for Budesonide with Eformoterol

insert after existing text in the columns in the order indicated:

C2680 Symptomatic treatment of chronic obstructive pulmonary disease (COPD), where the forced expiratory volume in 1 second (FEV1) is less than 50% predicted normal and there is a history of repeated exacerbations with significant symptoms despite regular beta-2 agonist bronchodilator therapy
  1. Schedule 4, Part 1, entry for Capecitabine

(a)        omit:

C2267 Adjuvant treatment of stage III (Dukes C) colon cancer, following complete resection of the primary tumour Compliance with Authority Required procedures

(b)        insert after existing text in the columns in the order indicated:

C3942 Adjuvant treatment of stage III (Dukes C) colon cancer, following complete resection of the primary tumour either as:
(a) monotherapy; or
(b) in combination with oxaliplatin
Compliance with Authority Required procedures
  1. Schedule 4, Part 1, entry for Cetuximab

substitute:

C2713

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Initial PBS-subsidised treatment, as monotherapy or in combination with an irinotecan based therapy, of a patient with a World Health Organisation performance status of 2 or less and with K-RAS wild type metastatic colorectal cancer after failure of first-line chemotherapy

Compliance with Authority Required procedures
C2714

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Continuing PBS-subsidised treatment, as monotherapy or in combination with an irinotecan based therapy, of a patient with K-RAS wild type metastatic colorectal cancer who has previously been issued with an authority prescription for cetuximab and who does not have progressive disease

Compliance with Authority Required procedures
C2715

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Initial treatment of stage III, IVa or IVb squamous cell cancer of the larynx, oropharynx or hypopharynx for the week prior to radiotherapy, where cisplatin is contraindicated according to the Therapeutic Goods Administration-approved Product Information

Compliance with Authority Required procedures
C3843

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Initial treatment of stage III, IVa or IVb squamous cell cancer of the larynx, oropharynx or hypopharynx, in combination with radiotherapy, where cisplatin is not tolerated

Compliance with Authority Required procedures
C3844

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Continuing treatment of stage III, IVa or IVb squamous cell cancer of the larynx, oropharynx or hypopharynx, in combination with radiotherapy, where cisplatin is either contraindicated or not tolerated

Compliance with Authority Required procedures
C3903

Where the patient is receiving treatment at/from a Public Hospital

Initial PBS-subsidised treatment, as monotherapy or in combination with an irinotecan based therapy, of a patient with a World Health Organisation performance status of 2 or less and with K-RAS wild type metastatic colorectal cancer after failure of first-line chemotherapy

Compliance with Authority Required procedures - Streamlined Authority Code 3903
C3904

Where the patient is receiving treatment at/from a Public Hospital

Continuing PBS-subsidised treatment, as monotherapy or in combination with an irinotecan based therapy, of a patient with K-RAS wild type metastatic colorectal cancer who has previously been issued with an authority prescription for cetuximab and who does not have progressive disease

Compliance with Authority Required procedures - Streamlined Authority Code 3904
C3919

Where the patient is receiving treatment at/from a Public Hospital

Initial treatment of stage III, IVa or IVb squamous cell cancer of the larynx, oropharynx or hypopharynx for the week prior to radiotherapy, where cisplatin is contraindicated according to the Therapeutic Goods Administration-approved Product Information

Compliance with Authority Required procedures - Streamlined Authority Code 3919
C3920

Where the patient is receiving treatment at/from a Public Hospital

Initial treatment of stage III, IVa or IVb squamous cell cancer of the larynx, oropharynx or hypopharynx, in combination with radiotherapy, where cisplatin is not tolerated

Compliance with Authority Required procedures - Streamlined Authority Code 3920
C3921

Where the patient is receiving treatment at/from a Public Hospital

Continuing treatment of stage III, IVa or IVb squamous cell cancer of the larynx, oropharynx or hypopharynx, in combination with radiotherapy, where cisplatin is either contraindicated or not tolerated

Compliance with Authority Required procedures - Streamlined Authority Code 3921
  1. Schedule 4, Part 1, entry for Dalteparin

insert after existing text in the columns in the order indicated:

C3688 P3688 Management of symptomatic venous thromboembolism in a patient with a solid tumour(s)
  1. Schedule 4, Part 1, entry for Darunavir

insert after existing text in the columns in the order indicated:

C3940

Where the patient is receiving treatment at/from a Private Hospital

Treatment of human immunodeficiency virus (HIV) infection, in addition to optimised background therapy in combination with other antiretroviral agents, and co-administered with 100 mg ritonavir in an antiretroviral experienced patient who, after at least one antiretroviral regimen, has experienced virological failure or clinical failure or genotypic resistance, and who has not demonstrated darunavir resistance associated mutations detected on resistance testing.
Virological failure is defined as a viral load greater than 400 copies per mL on two consecutive occasions, while clinical failure is linked to emerging signs and symptoms of progressing HIV infection or treatment-limiting toxicity

Compliance with Written or Telephone Authority Required procedures
C3941

Where the patient is receiving treatment at/from a Public Hospital

Treatment of human immunodeficiency virus (HIV) infection, in addition to optimised background therapy in combination with other antiretroviral agents, and co-administered with 100 mg ritonavir in an antiretroviral experienced patient who, after at least one antiretroviral regimen, has experienced virological failure or clinical failure or genotypic resistance, and who has not demonstrated darunavir resistance associated mutations detected on resistance testing.
Virological failure is defined as a viral load greater than 400 copies per mL on two consecutive occasions, while clinical failure is linked to emerging signs and symptoms of progressing HIV infection or treatment-limiting toxicity

Compliance with  Written or Telephone Authority Required procedures - Streamlined Authority Code 3941

  1. Schedule 4, Part 1, entry for Denosumab

substitute:

Denosumab C1035 Bone metastases from breast cancer Compliance with Authority Required procedures
C3579 Treatment as the sole PBS-subsidised anti-resorptive agent for osteoporosis in a woman aged 70 years of age or older with a bone mineral density T-score of -3.0 or less, and where the date, site (femoral neck or lumbar spine) and score of the qualifying bone mineral density measurement are documented in the patient's medical records when treatment is initiated Compliance with Authority Required procedures
C3580 Treatment as the sole PBS-subsidised anti-resorptive agent for established post-menopausal osteoporosis in a woman with fracture due to minimal trauma, where the fracture has been demonstrated radiologically and the year of plain x-ray or computed tomography scan or magnetic resonance imaging scan is documented in the patient's medical records when treatment is initiated, provided that if the fracture is a vertebral fracture, there is a 20% or greater reduction in height of the anterior or mid portion of the affected vertebral body relative to the posterior height of that body, or, a 20% or greater reduction in any of these heights compared to the vertebral body above or below the affected vertebral body Compliance with Authority Required procedures
C3881 Bone metastases from hormone-resistant prostate cancer. Compliance with Authority Required procedures
  1. Schedule 4, Part 1, entry for Docetaxel

substitute:

C3186 Advanced metastatic ovarian cancer after failure of prior therapy which includes a platinum compound Compliance with Authority Required procedures - Streamlined Authority Code 3186
C3884 Treatment of androgen independent (hormone refractory) metastatic carcinoma of the prostate in a patient with a Karnofsky performance-status score of at least 60%, where docetaxel is used as first-line chemotherapy and administered in three weekly cycles Compliance with Authority Required procedures - Streamlined Authority Code 3884
C3888 Neoadjuvant treatment of a patient with a World Health Organisation performance status of 1 or less, with inoperable Stage III, IVa or IVb squamous cell carcinoma of the oral cavity, larynx, oropharynx or hypopharynx, in combination with cisplatin and fluorouracil Compliance with Authority Required procedures - Streamlined Authority Code 3888
C3890 Locally advanced or metastatic non-small cell lung cancer Compliance with Authority Required procedures - Streamlined Authority Code 3890
C3892 Adjuvant treatment of operable breast cancer in combination with cyclophosphamide Compliance with Authority Required procedures - Streamlined Authority Code 3892
C3893 Advanced breast cancer after failure of prior therapy Compliance with Authority Required procedures - Streamlined Authority Code 3893
C3916 Adjuvant treatment of node-positive breast cancer in combination with an anthracycline and cyclophosphamide Compliance with Authority Required procedures - Streamlined Authority Code 3916
C3918 Treatment of HER2 positive early breast cancer in combination with trastuzumab Compliance with Authority Required procedures - Streamlined Authority Code 3918
  1. Schedule 4, Part 1, entry for Doxorubicin ─ Pegylated Liposomal

(a)        insert as first line in the column headed “Circumstances and Purposes” in respect of each of the Circumstances Codes: C1568; C1795; and C1796:

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

(b)        insert after existing text in the columns in the order indicated:

C3905

Where the patient is receiving treatment at/from a Public Hospital

Advanced epithelial ovarian cancer in women who have failed a first-line platinum-based chemotherapy regimen

Compliance with Authority Required procedures - Streamlined Authority Code 3905
C3910

Where the patient is receiving treatment at/from a Public Hospital

Metastatic breast cancer, as monotherapy, after failure of prior therapy which includes capecitabine and a taxane

Compliance with Authority Required procedures - Streamlined Authority Code 3910
C3911

Where the patient is receiving treatment at/from a Public Hospital

Metastatic breast cancer, as monotherapy, where therapy with capecitabine or a taxane is contraindicated

Compliance with Authority Required procedures - Streamlined Authority Code 3911
  1. Schedule 4, Part 1, entry for Fludarabine

insert after existing text in the columns in the order indicated:

C3887 B-cell chronic lymphocytic leukaemia in combination with cyclophosphamide where the patient has advanced disease (Binet Stage B or C) or evidence of progressive Stage A disease, and where:
(1) Stage A progressive disease is defined by at least 1 of the following:
— persistent rise in lymphocyte count with doubling time less than 12 months;
— a downward trend in haemoglobin or platelets, or both;
— more than 50% increase in the size of liver, spleen, or lymph nodes, or appearance of these signs if not previously present;
— constitutional symptoms attributable to disease; and
(2) the diagnosis of chronic lymphocytic leukaemia has been established based on:
(a) a lymphocytosis, with more than 5,000 million lymphocytes per L in the peripheral blood; and
(b) a clonal population of B-cells (CD5/CD19) documented by flow cytometry
Compliance with Authority Required procedures - Streamlined Authority Code 3887
  1. Schedule 4, Part 1, entry for Gemcitabine

substitute:

C1193

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Locally advanced or metastatic adenocarcinoma of the pancreas

Compliance with Authority Required procedures
C1194

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Locally advanced or metastatic non-small cell lung cancer

Compliance with Authority Required procedures
C1740

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Locally advanced or metastatic bladder cancer, in combination with cisplatin

Compliance with Authority Required procedures
C2069

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Advanced breast cancer in combination with paclitaxel after failure of prior therapy which includes an anthracycline

Compliance with Authority Required procedures
C2141

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Advanced epithelial ovarian cancer, in combination with carboplatin, in patients who relapse more than 6 months after platinum-based therapy

Compliance with Authority Required procedures
C3889

Where the patient is receiving treatment at/from a Public Hospital

Locally advanced or metastatic adenocarcinoma of the pancreas

Compliance with Authority Required procedures - Streamlined Authority Code 3889
C3890

Where the patient is receiving treatment at/from a Public Hospital

Locally advanced or metastatic non-small cell lung cancer

Compliance with Authority Required procedures - Streamlined Authority Code 3890
C3906

Where the patient is receiving treatment at/from a Public Hospital

Locally advanced or metastatic bladder cancer, in combination with cisplatin

Compliance with Authority Required procedures - Streamlined Authority Code 3906
C3913

Where the patient is receiving treatment at/from a Public Hospital

Advanced breast cancer in combination with paclitaxel after failure of prior therapy which includes an anthracycline

Compliance with Authority Required procedures - Streamlined Authority Code 3913
C3914

Where the patient is receiving treatment at/from a Public Hospital

Advanced epithelial ovarian cancer, in combination with carboplatin, in patients who relapse more than 6 months after platinum-based therapy

Compliance with Authority Required procedures - Streamlined Authority Code 3914
  1. Schedule 4, Part 1, after entry for Imiquimod

insert:

Indacaterol C3883 Chronic obstructive pulmonary disease
  1. Schedule 4, Part 1, entry for Interferon Alfa-2a

(a)        insert as first line in the column headed “Circumstances and Purposes” in respect of each of the Circumstances Codes: C1149; C1196; and C1234:

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

(b)           insert in numerical order for the column headed “Circumstances Code”:

C3180

Where the patient is receiving treatment at/from a Public Hospital

Hairy cell leukaemia

Compliance with Authority Required procedures - Streamlined Authority Code 3180

(c)           insert after existing text in the columns in the order indicated:

C3895

Where the patient is receiving treatment at/from a Public Hospital

Low grade non-Hodgkin's lymphoma with clinical features suggestive of a poor prognosis, in combination with anthracycline-based chemotherapy

Compliance with Authority Required procedures - Streamlined Authority Code 3895
C3899

Where the patient is receiving treatment at/from a Public Hospital

Myeloproliferative disease with excessive thrombocytosis

Compliance with Authority Required procedures - Streamlined Authority Code 3899
  1. Schedule 4, Part 1, entry for Interferon Alfa-2b

(a)        insert as first line in the column headed “Circumstances and Purposes” in respect of each of the Circumstances Codes: C1149; C1196; and C1206:

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

(b)           insert in numerical order for the column headed “Circumstances Code”:

C3180

Where the patient is receiving treatment at/from a Public Hospital

Hairy cell leukaemia

Compliance with Authority Required procedures - Streamlined Authority Code 3180

(c)           insert after existing text in the columns in the order indicated:

C3895

Where the patient is receiving treatment at/from a Public Hospital

Low grade non-Hodgkin's lymphoma with clinical features suggestive of a poor prognosis, in combination with anthracycline-based chemotherapy

Compliance with Authority Required procedures - Streamlined Authority Code 3895
C3898

Where the patient is receiving treatment at/from a Public Hospital

Maintenance treatment of multiple myeloma once remission has been achieved with chemotherapy

Compliance with Authority Required procedures - Streamlined Authority Code 3898
  1. Schedule 4, Part 1, after entry for Macrogol 3350

insert:

Magnesium C3937 Hypomagnesaemia in an Aboriginal or a Torres Strait Islander person Compliance with Authority Required procedures
C3938 Chronic renal disease in an Aboriginal or a Torres Strait Islander person Compliance with Authority Required procedures
  1. Schedule 4, Part 1, entry for Oxaliplatin

substitute:

Oxaliplatin C3900 Metastatic colorectal cancer in a patient with a World Health Organisation performance status of 2 or less, when used in combination with capecitabine Compliance with Authority Required procedures - Streamlined Authority Code 3900
C3901 Metastatic colorectal cancer in a patient with a World Health Organisation performance status of 2 or less, when used in combination with fluorouracil and folinic acid Compliance with Authority Required procedures - Streamlined Authority Code 3901
C3930 Adjuvant treatment of stage III (Dukes C) colon cancer following complete resection of the primary tumour used in combination with capecitabine Compliance with Authority Required procedures - Streamlined Authority Code 3930
C3939 Adjuvant treatment of stage III (Dukes C) colon cancer following complete resection of the primary tumour used in combination with 5-fluorouracil and folinic acid Compliance with Authority Required procedures - Streamlined Authority Code 3939
  1. Schedule 4, Part 1, after entry for Oxycodone

insert:

Oxycodone with naloxone C1062 Chronic severe disabling pain not responding to non-narcotic analgesics.
  1. Schedule 4, Part 1, entry for Paclitaxel

substitute:

Paclitaxel C3186 Advanced metastatic ovarian cancer after failure of prior therapy which includes a platinum compound Compliance with Authority Required procedures - Streamlined Authority Code 3186
C3890 Locally advanced or metastatic non-small cell lung cancer Compliance with Authority Required procedures - Streamlined Authority Code 3890
C3893 Advanced breast cancer after failure of prior therapy Compliance with Authority Required procedures - Streamlined Authority Code 3893
C3902 Primary treatment of ovarian cancer in combination with a platinum compound Compliance with Authority Required procedures - Streamlined Authority Code 3902
C3917 Adjuvant treatment of node-positive breast cancer administered sequentially to an anthracycline and cyclophosphamide Compliance with Authority Required procedures - Streamlined Authority Code 3917
C3918 Treatment of HER2 positive early breast cancer in combination with trastuzumab Compliance with Authority Required procedures - Streamlined Authority Code 3918
  1. Schedule 4, Part 1, entry for Paclitaxel, nanoparticle albumin-bound

substitute:

Paclitaxel, nanoparticle albumin-bound C3897 Metastatic breast cancer after failure of prior therapy Compliance with Authority Required procedures - Streamlined Authority Code 3897
  1. Schedule 4, Part 1, entry for Pemetrexed

substitute:

C2957

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Locally advanced or metastatic non-small cell lung cancer, after prior platinum-based chemotherapy, where the dose per treatment cycle does not exceed 500 mg per metre squared body surface area (BSA) and where the patient's BSA is included in the authority application

Compliance with Authority Required procedures

C2958

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Mesothelioma, in combination with cisplatin, where the dose per treatment cycle does not exceed 500 mg per metre squared body surface area (BSA) and where the patient's BSA is included in the authority application

Compliance with Authority Required procedures

C3885

Where the patient is receiving treatment at/from a Public Hospital

Locally advanced or metastatic non-small cell lung cancer, after prior platinum-based chemotherapy, where the dose per treatment cycle does not exceed 500 mg per metre squared body surface area (BSA) and where the patient's BSA is documented in the patient's medical records at the time the treatment cycle is initiated

Compliance with Authority Required procedures - Streamlined Authority Code 3885
C3886

Where the patient is receiving treatment at/from a Public Hospital

Mesothelioma, in combination with cisplatin, where the dose per treatment cycle does not exceed 500 mg per metre squared body surface area (BSA) and where the patient's BSA is documented in the patient's medical records at the time the treatment cycle is initiated

Compliance with Authority Required procedures - Streamlined Authority Code 3886
  1. Schedule 4, Part 1, entry for Ribavirin and Peginterferon Alfa-2b

insert after existing text in the columns in the order indicated:

C3948

Where the patient is receiving treatment at/from a Private Hospital

Patients naive to interferon based therapies (non-pegylated or pegylated)

Treatment, managed by an accredited treatment centre, of chronic hepatitis C in patients weighing at least 27 kg who have compensated liver disease and who have received no prior interferon alfa or peginterferon alfa treatment for hepatitis C and who satisfy all of the following criteria:
(1) Documented chronic hepatitis C infection (repeatedly anti-HCV positive and HCV RNA positive);
(2) Female patients of child-bearing age are not pregnant, not breast-feeding, and both patient and their partner are using effective forms of contraception (one for each partner). Male patients and their partners are using effective forms of contraception (one for each partner). Female partners of male patients are not pregnant.
For patients with genotype 2 or 3 hepatitis C without hepatic cirrhosis or bridging fibrosis, the treatment course is limited to 24 weeks. For hepatitis C patients with genotype 1, 4, 5 or 6 and those genotype 2 or 3 patients with hepatic cirrhosis or bridging fibrosis, the treatment course is limited to 48 weeks.
Patients with genotype 1, 4, 5 or 6 who are eligible for 48 weeks of treatment may only continue treatment after the first 12 weeks if the result of an HCV RNA quantitative assay (performed at the same laboratory using the same test) shows that the plasma HCV RNA has become undetectable or the viral load has decreased by at least a 2 log drop. (An HCV RNA assay at week 12 is unnecessary for genotype 2 and 3 patients because of the high likelihood of early viral response by week 12).
Patients with genotype 1, 4, 5 or 6 who are viral positive at week 12 but have attained at least a 2 log drop in viral load may only continue treatment after the first 24 weeks of treatment if plasma HCV RNA is not detectable by an HCV RNA qualitative assay at week 24. Similarly, genotype 2 or 3 patients with hepatic cirrhosis or bridging fibrosis may only continue treatment after the first 24 weeks if plasma HCV RNA is not detectable by an HCV RNA qualitative assay at week 24. An HCV RNA qualitative assay at week 24 is unnecessary for those patients with genotype 1, 4, 5 or 6 who became viral negative at week 12.

Compliance with Written or Telephone Authority Required procedures
C3949

Where the patient is receiving treatment at/from a public hospital

Patients naive to interferon based therapies (non-pegylated or pegylated)

Treatment, managed by an accredited treatment centre, of chronic hepatitis C in patients weighing at least 27 kg who have compensated liver disease and who have received no prior interferon alfa or peginterferon alfa treatment for hepatitis C and who satisfy all of the following criteria:
(1) Documented chronic hepatitis C infection (repeatedly anti-HCV positive and HCV RNA positive);
(2) Female patients of child-bearing age are not pregnant, not breast-feeding, and both patient and their partner are using effective forms of contraception (one for each partner). Male patients and their partners are using effective forms of contraception (one for each partner). Female partners of male patients are not pregnant.
For patients with genotype 2 or 3 hepatitis C without hepatic cirrhosis or bridging fibrosis, the treatment course is limited to 24 weeks. For hepatitis C patients with genotype 1, 4, 5 or 6 and those genotype 2 or 3 patients with hepatic cirrhosis or bridging fibrosis, the treatment course is limited to 48 weeks.
Patients with genotype 1, 4, 5 or 6 who are eligible for 48 weeks of treatment may only continue treatment after the first 12 weeks if the result of an HCV RNA quantitative assay (performed at the same laboratory using the same test) shows that the plasma HCV RNA has become undetectable or the viral load has decreased by at least a 2 log drop. (An HCV RNA assay at week 12 is unnecessary for genotype 2 and 3 patients because of the high likelihood of early viral response by week 12).
Patients with genotype 1, 4, 5 or 6 who are viral positive at week 12 but have attained at least a 2 log drop in viral load may only continue treatment after the first 24 weeks of treatment if plasma HCV RNA is not detectable by an HCV RNA qualitative assay at week 24. Similarly, genotype 2 or 3 patients with hepatic cirrhosis or bridging fibrosis may only continue treatment after the first 24 weeks if plasma HCV RNA is not detectable by an HCV RNA qualitative assay at week 24. An HCV RNA qualitative assay at week 24 is unnecessary for those patients with genotype 1, 4, 5 or 6 who became viral negative at week 12

Compliance with  Written or Telephone Authority Required procedures - Streamlined Authority Code 3949


  1. Schedule 4, Part 1, entry for Rituximab

substitute:

C1744

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Relapsed or refractory low-grade B-cell non-Hodgkin's lymphoma

Compliance with Authority Required procedures
C1745

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Relapsed or refractory follicular B-cell non-Hodgkin's lymphoma

Compliance with Authority Required procedures
C2068

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Treatment of previously untreated, CD20 positive, diffuse large B-cell non-Hodgkin's lymphoma, in combination with chemotherapy

Compliance with Authority Required procedures
C2386

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

Treatment of symptomatic patients with previously untreated, CD20 positive, Stage III or IV, follicular, B-cell non-Hodgkin's lymphoma in combination with chemotherapy

Compliance with Authority Required procedures
C3908

Where the patient is receiving treatment at/from a Public Hospital

Relapsed or refractory low-grade B-cell non-Hodgkin's lymphoma

Compliance with Authority Required procedures - Streamlined Authority Code 3908
C3909

Where the patient is receiving treatment at/from a Public Hospital

Relapsed or refractory follicular B-cell non-Hodgkin's lymphoma

Compliance with Authority Required procedures - Streamlined Authority Code 3909
C3912

Where the patient is receiving treatment at/from a Public Hospital

Treatment of previously untreated, CD20 positive, diffuse large B-cell non-Hodgkin's lymphoma, in combination with chemotherapy

Compliance with Authority Required procedures - Streamlined Authority Code 3912
C3915

Where the patient is receiving treatment at/from a Public Hospital

Treatment of symptomatic patients with previously untreated, CD20 positive, Stage III or IV, follicular, B-cell non-Hodgkin's lymphoma in combination with chemotherapy

Compliance with Authority Required procedures - Streamlined Authority Code 3915
C3931

Where the patient is receiving treatment in the community setting or at/from a Private Hospital

CD20 positive, chronic lymphocytic leukaemia, in combination with fludarabine and cyclophosphamide

Compliance with Authority Required procedures
C3932

Where the patient is receiving treatment at/from a Public Hospital

CD20 positive, chronic lymphocytic leukaemia, in combination with fludarabine and cyclophosphamide

Compliance with Authority Required procedures - Streamlined Authority Code 3932
  1. Schedule 4, Part 1, entry for Vinorelbine

(a)        omit:

C1741 Advanced breast cancer after failure of prior therapy which includes an anthracycline Compliance with Authority Required procedures

(b)        insert after existing text in the columns in the order indicated:

C3890 Locally advanced or metastatic non-small cell lung cancer Compliance with Authority Required procedures - Streamlined Authority Code 3890
C3907 Advanced breast cancer after failure of prior therapy which includes an anthracycline Compliance with Authority Required procedures - Streamlined Authority Code 3907
  1. Schedule 4, Part 1, entry for Zoledronic acid

(a)        omit:

C3287 Treatment as the sole PBS-subsidised anti-resorptive agent for osteoporosis in a patient aged 70 years of age or older with a bone mineral density T-score of -3.0 or less, where the date, site (femoral neck or lumbar spine) and score of the qualifying bone mineral density measurement are documented in the patient's medical records when treatment is initiated, and where PBS-subsidised treatment is limited to 3 doses per patient in their lifetime, administered as 1 dose each year for 3 years Compliance with Authority Required procedures
C3288 Treatment as the sole PBS-subsidised anti-resorptive agent for established osteoporosis in a patient with fracture due to minimal trauma, where the fracture has been demonstrated radiologically and the year of plain x-ray or computed tomography scan or magnetic resonance imaging scan is documented in the patient's medical records when treatment is initiated, provided that if the fracture is a vertebral fracture, there is a 20% or greater reduction in height of the anterior or mid portion of the affected vertebral body relative to the posterior height of that body, or, a 20% or greater reduction in any of these heights compared to the vertebral body above or below the affected vertebral body, and where PBS-subsidised treatment is limited to 3 doses per patient in their lifetime, administered as 1 dose each year for 3 years Compliance with Authority Required procedures
C3289 Treatment as the sole PBS-subsidised anti-resorptive agent for corticosteroid-induced osteoporosis in a patient currently on long-term (at least 3 months), high-dose (at least 7.5 mg per day prednisolone or equivalent) corticosteroid therapy with a bone mineral density T-score of -1.5 or less, and where the duration and dose of corticosteroid therapy, and the date, site (femoral neck or lumbar spine) and score of the qualifying bone mineral density measurement, are documented in the patient's medical records when treatment is initiated, and where PBS-subsidised treatment is limited to 3 doses per patient in their lifetime, administered as 1 dose each year for 3 years Compliance with Authority Required procedures

(b)        insert after existing text in the columns in the order indicated:

C3945 Treatment as the sole PBS-subsidised anti-resorptive agent for corticosteroid-induced osteoporosis in a patient currently on long-term (at least 3 months), high-dose (at least 7.5 mg per day prednisolone or equivalent) corticosteroid therapy with a bone mineral density T-score of -1.5 or less, and where the duration and dose of corticosteroid therapy, and the date, site (femoral neck or lumbar spine) and score of the qualifying bone mineral density measurement, are documented in the patient's medical records when treatment is initiated, and where PBS-subsidised treatment is limited to 1 dose per patient each year Compliance with Authority Required procedures - Streamlined Authority Code 3945

C3946 Treatment as the sole PBS-subsidised anti-resorptive agent for established osteoporosis in a patient with fracture due to minimal trauma, where the fracture has been demonstrated radiologically and the year of plain x-ray or computed tomography scan or magnetic resonance imaging scan is documented in the patient's medical records when treatment is initiated, provided that if the fracture is a vertebral fracture, there is a 20% or greater reduction in height of the anterior or mid portion of the affected vertebral body relative to the posterior height of that body, or, a 20% or greater reduction in any of these heights compared to the vertebral body above or below the affected vertebral body, and where PBS-subsidised treatment is limited to 1 dose per patient per year Compliance with Authority Required procedures - Streamlined Authority Code 3946


C3947 Treatment as the sole PBS-subsidised anti-resorptive agent for osteoporosis in a patient aged 70 years of age or older with a bone mineral density T-score of -3.0 or less, where the date, site (femoral neck or lumbar spine) and score of the qualifying bone mineral density measurement are documented in the patient's medical records when treatment is initiated, and where PBS-subsidised treatment is limited to 1 dose per patient each year Compliance with Authority Required procedures - Streamlined Authority Code 3947

1Note

All legislative instruments and compilations are registered on the Federal Register of Legislative Instruments kept under the Legislative Instruments Act 2003.

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